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Table 4 Algorithm for premixed insulin titration – adjustment according to postprandial glucose[54]

From: Evidence-based clinical use of insulin premixtures

Postprandial blood glucose (mg/dL)

Dose adjustment (units)

144-179

↑ by 1 unit

180-218

↑ by 2 units

219-258

↑ by 3 units

≥259

↑ by 4 units

  1. Postprandial adjustment: Adjust insulin dose administered in a given meal according to the 3-day average capillary blood glucose after the meal; postprandial was defined as <2 hours after the meal with a blood glucose goal of <144 mg/dL.