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Table 2 Comparison of study subjects’ characteristics between quartiles of CpG 94-102 %Meth levels measured in VAT

From: Comparison of the dipeptidyl peptidase-4 gene methylation levels between severely obese subjects with and without the metabolic syndrome

CpG94-102%Meth quartiles

Q1 [11.75−15.74[

Q2 [15.74−18.02[

Q3 [18.02−21.25[

Q4 [21.25−35.47]

P quartiles

P quartiles

 

n = 26

n = 26

n = 26

n = 26

Unadjusted

Adjusted

MetS phenotypes

      

MetS− (n = 72)

16 (0.22)

20 (0.28)

19 (0.26)

17 (0.24)

MetS+ (n = 32)

10 (0.31)

6 (0.19)

7 (0.22)

9 (0.28)

0.62

0.53

Waist circumference (cm)

135.6 ± 4.2

135.8 ± 4.2

133.3 ± 4.5

138.1 ± 3.7

0.87

0.78

Fasting glucose (mmol/L)

5.36 ± 0.13

5.08 ± 0.11

5.26 ± 0.17

5.44 ± 0.20

0.48

0.57

Triglycerides (mmol/L)

1.73 ± 0.15

1.24 ± 0.10

1.61 ± 0.30

1.91 ± 0.29

0.07

0.08

HDL-cholesterol (mmol/L)

1.37 ± 0.06

1.41 ± 0.06

1.37 ± 0.07

1.26 ± 0.06

0.42

0.62

SBP (mm Hg)

135.7 ± 3.0

138.0 ± 3.7

131.7 ± 3.34

131.1 ± 3.5

0.42

0.23

DBP (mm Hg)

83.0 ± 1.6

81.0 ± 2.3

81.9 ± 1.9

81.5 ± 2.3

0.78

0.56

Other phenotypes

      

LDL-cholesterol (mmol/L)

3.10 ± 0.13

2.68 ± 0.14

2.75 ± 0.17

3.00 ± 0.19

0.19

0.26

Total-cholesterol (mmol/L)

5.26 ± 0.13

4.65 ± 0.14

4.72 ± 0.18

5.10 ± 0.19

0.03

0.04

DPP4 mRNA in VAT (ratio)

3.92 ± 0.98

5.37 ± 1.24

2.99 ± 0.92

3.29 ± 0.81

0.13

0.13

  1. P-values shown are those obtained for the effect of%Meth quartiles when unadjusted or adjusted for potential confounding factors (age, sex and smoking for MetS and waist circumference; age, sex, smoking and waist circumference for the other phenotypes). Log10-transformed for DPP4 mRNA abundance and negative inverse-transformed for fasting glucose, triglycerides and DBP were used in the analyses. Mean ± s.e.m. or n are shown in the table.