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Table 2 Comparison of study subjects’ characteristics between quartiles of CpG 94-102 %Meth levels measured in VAT

From: Comparison of the dipeptidyl peptidase-4 gene methylation levels between severely obese subjects with and without the metabolic syndrome

CpG94-102%Meth quartiles Q1 [11.75−15.74[ Q2 [15.74−18.02[ Q3 [18.02−21.25[ Q4 [21.25−35.47] P quartiles P quartiles
  n = 26 n = 26 n = 26 n = 26 Unadjusted Adjusted
MetS phenotypes       
MetS− (n = 72) 16 (0.22) 20 (0.28) 19 (0.26) 17 (0.24)
MetS+ (n = 32) 10 (0.31) 6 (0.19) 7 (0.22) 9 (0.28) 0.62 0.53
Waist circumference (cm) 135.6 ± 4.2 135.8 ± 4.2 133.3 ± 4.5 138.1 ± 3.7 0.87 0.78
Fasting glucose (mmol/L) 5.36 ± 0.13 5.08 ± 0.11 5.26 ± 0.17 5.44 ± 0.20 0.48 0.57
Triglycerides (mmol/L) 1.73 ± 0.15 1.24 ± 0.10 1.61 ± 0.30 1.91 ± 0.29 0.07 0.08
HDL-cholesterol (mmol/L) 1.37 ± 0.06 1.41 ± 0.06 1.37 ± 0.07 1.26 ± 0.06 0.42 0.62
SBP (mm Hg) 135.7 ± 3.0 138.0 ± 3.7 131.7 ± 3.34 131.1 ± 3.5 0.42 0.23
DBP (mm Hg) 83.0 ± 1.6 81.0 ± 2.3 81.9 ± 1.9 81.5 ± 2.3 0.78 0.56
Other phenotypes       
LDL-cholesterol (mmol/L) 3.10 ± 0.13 2.68 ± 0.14 2.75 ± 0.17 3.00 ± 0.19 0.19 0.26
Total-cholesterol (mmol/L) 5.26 ± 0.13 4.65 ± 0.14 4.72 ± 0.18 5.10 ± 0.19 0.03 0.04
DPP4 mRNA in VAT (ratio) 3.92 ± 0.98 5.37 ± 1.24 2.99 ± 0.92 3.29 ± 0.81 0.13 0.13
  1. P-values shown are those obtained for the effect of%Meth quartiles when unadjusted or adjusted for potential confounding factors (age, sex and smoking for MetS and waist circumference; age, sex, smoking and waist circumference for the other phenotypes). Log10-transformed for DPP4 mRNA abundance and negative inverse-transformed for fasting glucose, triglycerides and DBP were used in the analyses. Mean ± s.e.m. or n are shown in the table.