Pleiotropic effects of rosuvastatin on the liver morphology. Mice were fed the standard chow (SC) or a high-fat diet (HF) for 15 weeks and then received five weeks of rosuvastatin treatment at doses of 10 mg/kg/day (HF-R10), 20 mg/kg/day (HF-R20), or 40 mg/kg/day (HF-R40). (A) Liver weight corrected by tibia length. (B) Hepatic triglyceride content. The symbols indicate a difference compared with [a] the SC group, [b] the HF group and [c] the HF-R10 group.