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Table 1 Physiological parameters

From: Heme oxygenase 1 improves glucoses metabolism and kidney histological alterations in diabetic rats

Groups CTL STZ STZ + HEME
  day 0 day 30 day 60 day 60 day 30 day 60 day 60 day 30 day 60
BW, g 278 ± 14 364 ± 24 436 ± 17 264 ± 10 241 ± 15* 255 ± 20* 247 ± 5 213 ± 18* 226 ± 18*
Uv, ml 13 ± 2 14 ± 1 12 ± 1 13.1 ± 1 69 ± 11* 57 ± 18* 16 ± 2 83 ± 5* 86 ± 2*
BG, mg/dl 86 ± 4 113 ± 12 109 ± 2 84 ± 4 470 ± 24* 554 ± 29* 80 ± 3 557 ± 27* 338 ± 24*#
U, mg/dl 45 ± 3 47 ± 4 44 ± 2 48 ± 2 91 ± 11* 88 ± 8* 48 ± 2 70 ± 5* 59 ± 6*#
ClCr, ml/min - - 1.02 ± 0.07 - - 0.12 ± 0.03* - - 0.28 ± 0.02*#
UA, mg/24h 0.50 ± 0.08 0.33 ± 0.06 0.28 ± 0.04 0.81 ± 0.09 1.67 ± 0.98 3.50 ± 1.04* 0.42 ± 0.05 1.05 ± 0.63 0.85 ± 0.42
UNaV, mEq/24h 0.7 ± 0.1 0.8 ± 0.1 0.7 ± 0.1 0.7 ± 0.1 2.8 ± 0.8* 0.9 ± 0.3 1.0 ± 0.1 2.4 ± 0.5* 1.4 ± 0.2*
  1. Data were expressed as the mean ± SEM. The significance level for a null hypothesis was set at 5% (p < 0.05). BW (body weight), Uv (urinary volume), BG (blood glucose), U (serum urea), ClCr (creatinine clearance), UA (urinary albumin) and UNaV (urinary sodium excretion) were analyzed in CTL, STZ and STZ+HEME groups. (*) versus CTL and (#) versus STZ.