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Figure 1 | Diabetology & Metabolic Syndrome

Figure 1

From: Heme oxygenase 1 improves glucoses metabolism and kidney histological alterations in diabetic rats

Figure 1

(A) Light microscopy of kidney sections stained with hematoxylin-eosin at 10x (HE 100), Picro-sirius red 20x (PC 200), 10x (polarized light, PC 100) and immunohistochemistry for HO-1 (200), iNOS (200) in control rats (CTL), rats treated with streptozotocin (STZ), and rats treated with STZ and daily injection of hemin (STZ+HEME). (B) Quantitative analyses of kidney sections stained for heme-oxygenase-1 (HO-1), induced nitric oxide synthase (iNOS) expressed as pixels/field, stained with HE (glomerulosclerosis) expressed as arbitrary units (AU). Data were expressed as the mean ± SEM. The significance level for a null hypothesis was set at 5% (p < 0.05) (*) significantly different in comparison to CTL group and (#) significantly different in comparison to STZ group.

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