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Figure 6 | Diabetology & Metabolic Syndrome

Figure 6

From: The effects of chronic AMPK activation on hepatic triglyceride accumulation and glycerol 3-phosphate acyltransferase activity with high fat feeding

Figure 6

Chronic activation of AMPK and sterol regulatory element binding protein-1c (SREBP-1c). a. Chronic activation of AMPK caused a reduction in the total abundance of uncleaved Sterol regulatory element binding protein-1c (SREBP-1c) in rats fed either chow or high fat diet (n = 3-5). Bands for all 4 groups were taken side by side with no interruption. Letters are used to represent significance. A significant main effect of AICAR was observed (p<0.05). Graph represents means ± SE. b. Chronic activation of AMPK caused a reduction in the total abundance of cleaved (65-68 kDa bands) SREBP-1c in the liver of rats fed either chow or high fat diet (n = 4-5). Bands for all 4 groups were taken side by side with no interruption. Letters are used to represent significance. A significant main effect of AICAR and high fat feeding was observed (p<0.05). Graph represents means ± SE.

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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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