Figure 5

Eukaryotic initiation factor 4E-binding protein (4EBP) following HF and AICAR treatments. a. Total Eukaryotic initiation factor 4E-binding protein (4EBP) results show an increase with the treatment of AICAR (n = 4-5). Bands for all 4 groups were taken side by side with no interruption Asterisk (*) denotes a main effect of AICAR treatment (P<0.05). Graph represents means ± SE. b Eukaryotic initiation factor 4E-binding protein (4EBP) phosphorylation (percentage of the total protein in the 2 hypophosphorylated bands compared to total) showed an increased phosphorylation with AICAR treatment (n = 4-5). Bands for all 4 groups were taken side by side with no interruption. Letters are used to represent significance; same letter means no significant difference (P < 0.05). Graph represents means ± SE.