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Table 2 Analysis (by qRT-PCR) of the expression of additional genes identified as Pioglitazone targets by network analysis after 24-hour exposure to the drug at 5.6 mM and 23 mM glucose concentrations

From: Apoptosis rate and transcriptional response of pancreatic islets exposed to the PPAR gamma agonist Pioglitazone

  Genes FC p-value
5,6 mM Srebf1 1.3 0.02
23 mM Aldob −1.8 0.05
Lipe 2.0 0.03
Myc 2.0 0.04
Scd2 1.5 0.01
Srebf1 1.3 0.03
  Tnf 3.6 0.05
  1. Positive and negative FC (fold-change) represent, respectively, genes upregulated and downregulated by Pioglitazone.
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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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