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Table 2 Analysis (by qRT-PCR) of the expression of additional genes identified as Pioglitazone targets by network analysis after 24-hour exposure to the drug at 5.6 mM and 23 mM glucose concentrations

From: Apoptosis rate and transcriptional response of pancreatic islets exposed to the PPAR gamma agonist Pioglitazone

 

Genes

FC

p-value

5,6 mM

Srebf1

1.3

0.02

23 mM

Aldob

−1.8

0.05

Lipe

2.0

0.03

Myc

2.0

0.04

Scd2

1.5

0.01

Srebf1

1.3

0.03

 

Tnf

3.6

0.05

  1. Positive and negative FC (fold-change) represent, respectively, genes upregulated and downregulated by Pioglitazone.