Figure 2
From: Goettingen Minipigs (GMP): Comparison of Two Different Models for Inducing Diabetes
Intravenous glucose tolerance test (IVGTT) in normoglycemic GMP (n = 3) with subsequent hyperglycemic clamp and arginine injection (blue curve). Red curve: C-peptide levels during IVGTT; green curve: insulin levels during IVGTT. Glucose injection at time point t = 0: 0.5 g/kg bw; glucose injection at t = +60 min: 0.6 g/kg; continual glucose infusion from t = +60 min to t = +100 min: 2 g/kg per hour; arginine injection at t = +90 min: 67 mg/kg.