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Table 2 Mean (SD) or median (interquartile interval) values of variables and variation after 9 months of lifestyle intervention according to SNP TNF −308 G/A genotypes

From: Associations of the TNF-alpha -308 G/A, IL6 -174 G/C and AdipoQ 45 T/G polymorphisms with inflammatory and metabolic responses to lifestyle intervention in Brazilians at high cardiometabolic risk

  GG (n = 107) AA + GA (n = 28)
  Baseline 9 months p Baseline 9 months p
Energy intake (Kcal/day) 1851.6(685.0) 1555.4(580.6) .001 1633.6(620.9) 1449.0(488.5) .006
Total physical activity (min/wk) 167(60, 278) 205(75, 305) .002 140(30, 210) 210(60, 400) .021
Weight (kg) 79.0(15.4) 77.1(15.2) .006 76.5(16.6) 74.8(16.9) .006
Waist circumference (cm) 99.2(12.1) 98.3(11.7) .029 98.0(13.0) 96.9(13.6) .205
Fasting glucose (mg/dL) 97.8(11.1) 96.2(13.1) .233 103.9(11.2)† 97.1(9.9) .007
Triglycerides (mg/dL) 159.1(68.0) 154.2(74.6) .428 138.2(56.2) 141.7(61.9) .689
Total cholesterol (mg/dL) 200.9(42.8) 197.3(43.3) .413 202.2(47.4) 197.1(45.9) .559
HDL-c (mg/dL) 41.7(12.3) 46.7(13.2) .020 45.5(12.7) 46.3(10.0) .778
LDL-c (mg/dL) 127.3(38.9) 120.1(38.2) .097 126.8(44.6) 122.4(41.3) .647
Apolipoprotein B (mg/dL) 95.6(22.4) 84.8(23.8) .004 95.3(23.4) 82.5(25.5) .004
Apolipoprotein A1 (mg/dL) 135.8(17.8) 140.8(20.1) .005 139.7(21.7) 142.0(19.0) .443
Insulin* (uUl/L) 9.8(6.1, 12.0) 6.9(4.3, 10.5) .009 5.6(4.0, 10.7)† 5.2(3.1, 8.8) .151
Adiponectin* (ng/dL) 11.8(7.5, 18.7) 16.2(11.3, 19.4) .019 11.7(7.3, 19.1) 16.2(12.2, 20.9) .020
Interleukin 6* (pg/dL) 2.4(1.3, 3.7) 3.2(2.0, 5.2) .013 2.4(1.1, 4.9) 4.2(2.4, 9.4) .006
C-reactive protein* (mg/dL) 0.37(0.19, 0.59) 0.25(0.05, 0.55) .001 0.36(0.13, 0.94) 0.32(0.15, 0.89) .009
TNF-α** (pg/dL) 10.8(9.0, 13.2) 8.7(7.2, 10.8) .020 11.3(9.4, 13.9) 8.9(6.9, 10.2) .016
  1. *log-transformed for analysis.
  2. **Non-parametric test.
  3. † p < 0.05 versus GG.
  4. TNF-α: Tumor necrosis factor alpha.