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Table 2 Comparison of groups categorized based on the presence of elevated LDL-C levels and hypertriglyceridemia

From: Fatty liver in men is associated with high serum levels of small, dense low-density lipoprotein cholesterol

Elevated LDL-C levels/hypertriglyceridemia

Group A

Group B

Group C

Group D

P value

(−)/(−) (n = 216)

(+)/(−) (n = 120)

(−)/(+) (n = 95)

(+)/(+) (n = 45)

Lipid profiles

     

 TG (mg/dl)

91.1 [85.1−96.7]

98.1 [90.5−105.6]

229.3 [220.8−237.8]

219.0 [206.7−231.4]

< 0.001

 HDL-C (mg/dl)

59.3 [57.6−61.1]

56.8 [54.4−59.1]

49.3 [46.7−52.0]

48.9 [45.1−52.7]

< 0.001

 LDL-C (mg/dl)

114.2 [111.8−116.7]

162.5 [159.2−165.8]

112.1 [108.4−115.8]

159.1 [153.8−164.5]

< 0.001

 Sd-LDL-C (mg/dl)

33.8 [31.9−35.6]

49.6 [47.2−52.1]

51.9 [49.2−54.7]

68.5 [64.5−72.5]

< 0.001

 Sd-LDL-C/LDL-C

0.30 [0.28−0.31]

0.30 [0.29−0.32]

0.47 [0.45−0.48]

0.43 [0.40−0.46]

< 0.001

 TC (mg/dl)

191.8 [188.7−194.8]

238.9 [234.8−243.1]

207.3 [202.7−212.0]

251.8 [245.1−258.6]

< 0.001

 Apolipoprotein B (mg/dl)

82.8 [75.5−80.4]

112.6 [110.3−114.9]

99.4 [96.8−102.0]

126.3 [122.5−130.1]

< 0.001

Demographics, clinical characteristics, and laboratory data

 Age (years)

57.4 [56.2−58.7]

56.1 [54.4−57.8]

54.3 [52.4−56.3]

51.5 [48.7−54.3]

< 0.001

 BMI (kg/m2)

23.6 [23.2−24.0]

24.0 [23.4−24.5]

25.1 [24.5−25.7]

25.7 [24.8−26.6]

< 0.001

 Obesity (% of subjects)

31.0

30.8

46.3

62.2

< 0.001

 Glucose (mg/dl)

103.8 [101.4−106.1]

105.2 [102.1−108.4]

113.5 [110.0−117.1]

111.5 [106.4−116.7]

< 0.001

Hyperglycemia

     

 (% of subjects)

22.7

27.5

37.9

44.4

0.004

 ALT (IU/L)

24.3 [22.0−26.6]

27.4 [24.3−30.5]

34.4 [30.9−37.9]

34.6 [29.5−39.6]

< 0.001

 γ-GTP (IU/L)

35.3 [29.4−41.2]

38.6 [30.7−46.5]

70.0 [61.2−78.9]

59.6 [46.8−72.5]

< 0.001

 Fatty liver (% of subjects)

25.9

43.3

61.1

53.3

< 0.001

Hypertension

     

 (% of subjects)

53.7

54.2

57.9

55.6

0.919

Current alcohol consumption

     

 (% of subjects)

38.4

54.2

46.3

33.3

0.153

Current smokers

     

 (% of subjects)

28.7

30.0

28.4

24.4

0.919

  1. Data are expressed as means [95% CIs] or percentages. $, LDL-C levels were calculated using the Friedwald formula.
  2. Continuous variables were compared by ANOVA and categorical variables were compared by Chi-square tests.