Figure 6From: Diet high in fat and sucrose induces rapid onset of obesity-related metabolic syndrome partly through rapid response of genes involved in lipogenesis, insulin signalling and inflammation in miceEffect of the HF–HS diet on WAT genes involved in lipogenesis and inflammation. (A) mRNA expression of genes related to lipogenesis: SREBP1c, SCD-1, and FAS, and of the lipolysis-related gene, LPL. (B) mRNA expression of genes related to inflammation: MAC1, CD68, and MMP3. HF–HS diet: high fat–high sucrose diet. C57BL/6 J mice were fed standard chow diet or the HF–HS diet (milk fat 21% and sucrose 34%) for 2 or 4 weeks. Values are the mean ± SE and are relative to control values, which were set at 1.0. n = 6. * P < 0.05, ** P < 0.01, *** P < 0.001.Back to article page