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Figure 6 | Diabetology & Metabolic Syndrome

Figure 6

From: Diet high in fat and sucrose induces rapid onset of obesity-related metabolic syndrome partly through rapid response of genes involved in lipogenesis, insulin signalling and inflammation in mice

Figure 6

Effect of the HF–HS diet on WAT genes involved in lipogenesis and inflammation. (A) mRNA expression of genes related to lipogenesis: SREBP1c, SCD-1, and FAS, and of the lipolysis-related gene, LPL. (B) mRNA expression of genes related to inflammation: MAC1, CD68, and MMP3. HF–HS diet: high fat–high sucrose diet. C57BL/6 J mice were fed standard chow diet or the HF–HS diet (milk fat 21% and sucrose 34%) for 2 or 4 weeks. Values are the mean ± SE and are relative to control values, which were set at 1.0. n = 6. * P < 0.05, ** P < 0.01, *** P < 0.001.

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