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Table 3 Circulating cytokine, adipokine and acute phase reactant concentrations

From: Preliminary evidence for obesity-associated insulin resistance in adolescents without elevations of inflammatory cytokines

 

Lean

Obese

p-value

TNFα (pg/ml)

3.4 ± 2.1

3.5 ± 2.0

0.900

IL-6 (pg/ml)

8.1 ± 6.8

9.3 ± 8.4

0.588

IFN-γ (pg/ml)

14.1 ± 12.8

11.4 ± 8.0

0.321

IL-4 (pg/ml)

77.4 ± 54.8

79.5 ± 49.1

0.877

IL-10 (pg/ml)

22.5 ± 21.4

26.3 ± 46.3

0.715

Leptin (ng/ml)

10.9 ± 11.1

38.1 ± 25.6

0.000**

Adiponectin (ng/ml)

766.8 ± 165.9

112.0 ± 233.1

0.652

Resistin (pg/ml)

102.8 ± 65.3

119.2 ± 117.3

0.538

Acute phase reactants

   

CRP (mg/L)

0.5 ± 0.4

3.3 ± 2.2

0.000**

Fibrinogen (mg/L)

278.2 ± 33.3

327.9 ± 54.4

0.000**

  1. **denotes a p-value of ≤0.010.
  2. Tumor necrosis factor (TNF); interferon (IFN); interleukin (IL); C-reactive protein (CRP).