TY - JOUR AU - Uysal, K. T. AU - Wiesbrock, S. M. AU - Marino, M. W. AU - Hotamisligil, G. S. PY - 1997 DA - 1997// TI - Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function JO - Nature VL - 6651 ID - Uysal1997 ER - TY - JOUR AU - Pi-Sunyer, F. X. PY - 2002 DA - 2002// TI - The medical risks of obesity JO - Obes Surg VL - 12 UR - https://doi.org/10.1007/BF03342140 DO - 10.1007/BF03342140 ID - Pi-Sunyer2002 ER - TY - JOUR AU - Cohen, J. C. AU - Horton, J. D. AU - Hobbs, H. H. PY - 2011 DA - 2011// TI - Human fatty liver disease: old questions and new insights JO - Science VL - 6037 UR - https://doi.org/10.1126/science.1204265 DO - 10.1126/science.1204265 ID - Cohen2011 ER - TY - JOUR AU - de Onis, M. AU - Blossner, M. AU - Borghi, E. PY - 2010 DA - 2010// TI - Global prevalence and trends of overweight and obesity among preschool children JO - Am J Clin Nutr VL - 5 UR - https://doi.org/10.3945/ajcn.2010.29786 DO - 10.3945/ajcn.2010.29786 ID - de Onis2010 ER - TY - JOUR AU - Dietz, W. H. PY - 1998 DA - 1998// TI - Health consequences of obesity in youth: childhood predictors of adult disease JO - Pediatrics VL - 3 ID - Dietz1998 ER - TY - JOUR AU - Wellen, K. E. AU - Hotamisligil, G. S. PY - 2003 DA - 2003// TI - Obesity-induced inflammatory changes in adipose tissue JO - J Clin Invest VL - 12 UR - https://doi.org/10.1172/JCI20514 DO - 10.1172/JCI20514 ID - Wellen2003 ER - TY - JOUR AU - Hotamisligil, G. S. PY - 2003 DA - 2003// TI - Inflammatory pathways and insulin action JO - Int J Obes Relat Metab Disord VL - 27 UR - https://doi.org/10.1038/sj.ijo.0802502 DO - 10.1038/sj.ijo.0802502 ID - Hotamisligil2003 ER - TY - JOUR AU - Galic, S. AU - Oakhill, J. S. AU - Steinberg, G. R. PY - 2010 DA - 2010// TI - Adipose tissue as an endocrine organ JO - Mol Cell Endocrinol VL - 2 UR - https://doi.org/10.1016/j.mce.2009.08.018 DO - 10.1016/j.mce.2009.08.018 ID - Galic2010 ER - TY - JOUR AU - Tam, L. S. AU - Tomlinson, B. AU - Chu, T. T. AU - Li, T. K. AU - Li, E. K. PY - 2007 DA - 2007// TI - Impact of TNF inhibition on insulin resistance and lipids levels in patients with rheumatoid arthritis JO - Clin Rheumatol VL - 9 UR - https://doi.org/10.1007/s10067-007-0539-8 DO - 10.1007/s10067-007-0539-8 ID - Tam2007 ER - TY - JOUR AU - Olszanecka-Glinianowicz, M. AU - Kocelak, P. AU - Janowska, J. AU - Skorupa, A. AU - Nylec, M. AU - Zahorska-Markiewicz, B. PY - 2011 DA - 2011// TI - Plasma visfatin and tumor necrosis factor-alpha (TNF-alpha) levels in metabolic syndrome JO - Kardiol Pol VL - 8 ID - Olszanecka-Glinianowicz2011 ER - TY - JOUR AU - Gnacinska, M. AU - Malgorzewicz, S. AU - Stojek, M. AU - Lysiak-Szydlowska, W. AU - Sworczak, K. PY - 2009 DA - 2009// TI - Role of adipokines in complications related to obesity: a review JO - Adv Med Sci VL - 2 ID - Gnacinska2009 ER - TY - JOUR AU - Ahima, R. S. AU - Flier, J. S. PY - 2000 DA - 2000// TI - Adipose tissue as an endocrine organ JO - Trends Endocrinol Metab VL - 8 UR - https://doi.org/10.1016/S1043-2760(00)00301-5 DO - 10.1016/S1043-2760(00)00301-5 ID - Ahima2000 ER - TY - JOUR AU - Kershaw, E. E. AU - Flier, J. S. PY - 2004 DA - 2004// TI - Adipose tissue as an endocrine organ JO - J Clin Endocrinol Metab VL - 6 UR - https://doi.org/10.1210/jc.2004-0395 DO - 10.1210/jc.2004-0395 ID - Kershaw2004 ER - TY - JOUR AU - Hotamisligil, G. S. AU - Arner, P. AU - Caro, J. F. AU - Atkinson, R. L. AU - Spiegelman, B. M. PY - 1995 DA - 1995// TI - Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance JO - J Clin Invest VL - 5 UR - https://doi.org/10.1172/JCI117936 DO - 10.1172/JCI117936 ID - Hotamisligil1995 ER - TY - JOUR AU - Tuttolomondo, A. AU - Di Raimondo, D. AU - Pecoraro, R. AU - Serio, A. AU - D'Aguanno, G. AU - Pinto, A. PY - 2010 DA - 2010// TI - Immuneinflammatory markers and arterial stiffness indexes in subjects with acute ischemic stroke JO - Atherosclerosis VL - 1 UR - https://doi.org/10.1016/j.atherosclerosis.2010.08.065 DO - 10.1016/j.atherosclerosis.2010.08.065 ID - Tuttolomondo2010 ER - TY - JOUR AU - Lee, I. S. AU - Shin, G. AU - Choue, R. PY - 2010 DA - 2010// TI - Shifts in diet from high fat to high carbohydrate improved levels of adipokines and pro-inflammatory cytokines in mice fed a high-fat diet JO - Endocr J VL - 1 UR - https://doi.org/10.1507/endocrj.K09E-046 DO - 10.1507/endocrj.K09E-046 ID - Lee2010 ER - TY - JOUR AU - Rosenbaum, M. AU - Leibel, R. L. PY - 1999 DA - 1999// TI - The role of leptin in human physiology JO - N Engl J Med VL - 12 UR - https://doi.org/10.1056/NEJM199909163411211 DO - 10.1056/NEJM199909163411211 ID - Rosenbaum1999 ER - TY - JOUR AU - Chiang, D. J. AU - Pritchard, M. T. AU - Nagy, L. E. PY - 2011 DA - 2011// TI - Obesity, diabetes mellitus, and liver fibrosis JO - Am J Physiol Gastrointest Liver Physiol VL - 5 UR - https://doi.org/10.1152/ajpgi.00426.2010 DO - 10.1152/ajpgi.00426.2010 ID - Chiang2011 ER - TY - JOUR AU - Sun, K. AU - Kusminski, C. M. AU - Scherer, P. E. PY - 2011 DA - 2011// TI - Adipose tissue remodeling and obesity JO - J Clin Invest VL - 6 UR - https://doi.org/10.1172/JCI45887 DO - 10.1172/JCI45887 ID - Sun2011 ER - TY - JOUR AU - Libby, P. PY - 2002 DA - 2002// TI - Inflammation in atherosclerosis JO - Nature VL - 6917 UR - https://doi.org/10.1038/nature01323 DO - 10.1038/nature01323 ID - Libby2002 ER - TY - JOUR AU - Goldberg, R. B. PY - 2009 DA - 2009// TI - Cytokine and cytokine-like inflammation markers, endothelial dysfunction, and imbalanced coagulation in development of diabetes and its complications JO - J Clin Endocrinol Metab VL - 9 UR - https://doi.org/10.1210/jc.2008-2534 DO - 10.1210/jc.2008-2534 ID - Goldberg2009 ER - TY - JOUR AU - Miyamoto, T. AU - Carrero, J. J. AU - Stenvinkel, P. PY - 2011 DA - 2011// TI - Inflammation as a risk factor and target for therapy in chronic kidney disease JO - Curr Opin Nephrol Hypertens VL - 6 UR - https://doi.org/10.1097/MNH.0b013e32834ad504 DO - 10.1097/MNH.0b013e32834ad504 ID - Miyamoto2011 ER - TY - JOUR AU - Astrand, O. AU - Carlsson, M. AU - Nilsson, I. AU - Lindstrom, T. AU - Borga, M. AU - Nystrom, F. H. PY - 2010 DA - 2010// TI - Weight gain by hyperalimentation elevates C-reactive protein levels but does not affect circulating levels of adiponectin or resistin in healthy subjects JO - Eur J Endocrinol VL - 6 UR - https://doi.org/10.1530/EJE-10-0763 DO - 10.1530/EJE-10-0763 ID - Astrand2010 ER - TY - JOUR AU - Warnberg, J. AU - Moreno, L. A. AU - Mesana, M. I. AU - Marcos, A. PY - 2004 DA - 2004// TI - Inflammatory mediators in overweight and obese Spanish adolescents. The AVENA Study JO - Int J Obes Relat Metab Disord VL - 28 UR - https://doi.org/10.1038/sj.ijo.0802809 DO - 10.1038/sj.ijo.0802809 ID - Warnberg2004 ER - TY - JOUR AU - Weiss, R. AU - Taksali, S. E. AU - Dufour, S. AU - Yeckel, C. W. AU - Papademetris, X. AU - Cline, G. PY - 2005 DA - 2005// TI - The "obese insulin- sensitive" adolescent: importance of adiponectin and lipid partitioning JO - J Clin Endocrinol Metab VL - 6 UR - https://doi.org/10.1210/jc.2004-2305 DO - 10.1210/jc.2004-2305 ID - Weiss2005 ER - TY - JOUR AU - Cook, S. AU - Weitzman, M. AU - Auinger, P. AU - Nguyen, M. AU - Dietz, W. H. PY - 2003 DA - 2003// TI - Prevalence of a metabolic syndrome phenotype in adolescents: findings from the third National Health and Nutrition Examination Survey, 1988–1994 JO - Arch Pediatr Adolesc Med VL - 8 UR - https://doi.org/10.1001/archpedi.157.8.821 DO - 10.1001/archpedi.157.8.821 ID - Cook2003 ER - TY - JOUR AU - Kerkhof, H. J. AU - Bierma-Zeinstra, S. M. AU - Castano-Betancourt, M. C. AU - de Maat, M. P. AU - Hofman, A. AU - Pols, H. A. PY - 2010 DA - 2010// TI - Serum C reactive protein levels and genetic variation in the CRP gene are not associated with the prevalence, incidence or progression of osteoarthritis independent of body mass index JO - Ann Rheum Dis VL - 11 UR - https://doi.org/10.1136/ard.2009.125260 DO - 10.1136/ard.2009.125260 ID - Kerkhof2010 ER - TY - JOUR AU - Mather, K. J. AU - Hunt, A. E. AU - Steinberg, H. O. AU - Paradisi, G. AU - Hook, G. AU - Katz, A. PY - 2001 DA - 2001// TI - Repeatability characteristics of simple indices of insulin resistance: implications for research applications JO - J Clin Endocrinol Metab VL - 11 UR - https://doi.org/10.1210/jcem.86.11.7880 DO - 10.1210/jcem.86.11.7880 ID - Mather2001 ER - TY - JOUR AU - Keskin, M. AU - Kurtoglu, S. AU - Kendirci, M. AU - Atabek, M. E. AU - Yazici, C. PY - 2005 DA - 2005// TI - Homeostasis model assessment is more reliable than the fasting glucose/insulin ratio and quantitative insulin sensitivity check index for assessing insulin resistance among obese children and adolescents JO - Pediatrics VL - 4 UR - https://doi.org/10.1542/peds.2004-1921 DO - 10.1542/peds.2004-1921 ID - Keskin2005 ER - TY - JOUR AU - Tam, C. S. AU - Clement, K. AU - Baur, L. A. AU - Tordjman, J. PY - 2010 DA - 2010// TI - Obesity and low-grade inflammation: a paediatric perspective JO - Obes Rev VL - 2 UR - https://doi.org/10.1111/j.1467-789X.2009.00674.x DO - 10.1111/j.1467-789X.2009.00674.x ID - Tam2010 ER - TY - JOUR AU - Xu, H. AU - Barnes, G. T. AU - Yang, Q. AU - Tan, G. AU - Yang, D. AU - Chou, C. J. PY - 2003 DA - 2003// TI - Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance JO - J Clin Invest VL - 12 UR - https://doi.org/10.1172/JCI200319451 DO - 10.1172/JCI200319451 ID - Xu2003 ER - TY - JOUR AU - Weisberg, S. P. AU - McCann, D. AU - Desai, M. AU - Rosenbaum, M. AU - Leibel, R. L. AU - Ferrante, A. W. PY - 2003 DA - 2003// TI - Obesity is associated with macrophage accumulation in adipose tissue JO - J Clin Invest VL - 12 UR - https://doi.org/10.1172/JCI200319246 DO - 10.1172/JCI200319246 ID - Weisberg2003 ER - TY - JOUR AU - Ng, P. M. AU - Le Saux, A. AU - Lee, C. M. AU - Tan, N. S. AU - Lu, J. AU - Thiel, S. PY - 2007 DA - 2007// TI - C-reactive protein collaborates with plasma lectins to boost immune response against bacteria JO - EMBO J VL - 14 UR - https://doi.org/10.1038/sj.emboj.7601762 DO - 10.1038/sj.emboj.7601762 ID - Ng2007 ER - TY - JOUR AU - Conigrave, K. M. AU - Davies, P. AU - Haber, P. AU - Whitfield, J. B. PY - 2003 DA - 2003// TI - Traditional markers of excessive alcohol use JO - Addiction VL - 98 UR - https://doi.org/10.1046/j.1359-6357.2003.00581.x DO - 10.1046/j.1359-6357.2003.00581.x ID - Conigrave2003 ER - TY - JOUR AU - Carey, E. AU - Carey, W. D. PY - 2010 DA - 2010// TI - Noninvasive tests for liver disease, fibrosis, and cirrhosis: Is liver biopsy obsolete? JO - Cleve Clin J Med VL - 8 UR - https://doi.org/10.3949/ccjm.77a.09138 DO - 10.3949/ccjm.77a.09138 ID - Carey2010 ER - TY - JOUR AU - Schalkwijk, C. G. AU - Brouwers, O. AU - Stehouwer, C. D. PY - 2008 DA - 2008// TI - Modulation of insulin action by advanced glycation endproducts: a new player in the field JO - Horm Metab Res VL - 9 UR - https://doi.org/10.1055/s-0028-1082085 DO - 10.1055/s-0028-1082085 ID - Schalkwijk2008 ER - TY - JOUR AU - Lumeng, C. N. AU - Deyoung, S. M. AU - Bodzin, J. L. AU - Saltiel, A. R. PY - 2007 DA - 2007// TI - Increased inflammatory properties of adipose tissue macrophages recruited during diet-induced obesity JO - Diabetes VL - 1 UR - https://doi.org/10.2337/db06-1076 DO - 10.2337/db06-1076 ID - Lumeng2007 ER - TY - JOUR AU - Lumeng, C. N. AU - Bodzin, J. L. AU - Saltiel, A. R. PY - 2007 DA - 2007// TI - Obesity induces a phenotypic switch in adipose tissue macrophage polarization JO - J Clin Invest VL - 1 UR - https://doi.org/10.1172/JCI29881 DO - 10.1172/JCI29881 ID - Lumeng2007 ER - TY - JOUR AU - Wellen, K. E. AU - Hotamisligil, G. S. PY - 2005 DA - 2005// TI - Inflammation, stress, and diabetes JO - J Clin Invest VL - 5 UR - https://doi.org/10.1172/JCI200525102 DO - 10.1172/JCI200525102 ID - Wellen2005 ER - TY - JOUR AU - Neels, J. G. AU - Olefsky, J. M. PY - 2006 DA - 2006// TI - Inflamed fat: what starts the fire? JO - J Clin Invest VL - 1 ID - Neels2006 ER - TY - JOUR AU - Barrachina, M. D. AU - Martinez, V. AU - Wei, J. Y. AU - Tache, Y. PY - 1997 DA - 1997// TI - Leptin-induced decrease in food intake is not associated with changes in gastric emptying in lean mice JO - Am J Physiol VL - 3 ID - Barrachina1997 ER - TY - JOUR AU - Peters, J. H. AU - Simasko, S. M. AU - Ritter, R. C. PY - 2006 DA - 2006// TI - Modulation of vagal afferent excitation and reduction of food intake by leptin and cholecystokinin JO - Physiol Behav VL - 4 UR - https://doi.org/10.1016/j.physbeh.2006.06.017 DO - 10.1016/j.physbeh.2006.06.017 ID - Peters2006 ER - TY - JOUR AU - Bjorbaek, C. PY - 2009 DA - 2009// TI - Central Leptin Receptor Action and Resistance in Obesity JO - J Invest Med VL - 7 ID - Bjorbaek2009 ER - TY - JOUR AU - Das, U. N. PY - 2010 DA - 2010// TI - Obesity: genes, brain, gut, and environment JO - Nutrition VL - 5 UR - https://doi.org/10.1016/j.nut.2009.09.020 DO - 10.1016/j.nut.2009.09.020 ID - Das2010 ER - TY - JOUR AU - Holland, W. L. AU - Bikman, B. T. AU - Wang, L. P. AU - Yuguang, G. AU - Sargent, K. M. AU - Bulchand, S. PY - 2011 DA - 2011// TI - Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in mice JO - J Clin Invest VL - 5 UR - https://doi.org/10.1172/JCI43378 DO - 10.1172/JCI43378 ID - Holland2011 ER - TY - JOUR AU - Hauner, H. AU - Bender, M. AU - Haastert, B. AU - Hube, F. PY - 1998 DA - 1998// TI - Plasma concentrations of soluble TNF-alpha receptors in obese subjects JO - Int J Obes Relat Metab Disord VL - 12 UR - https://doi.org/10.1038/sj.ijo.0800773 DO - 10.1038/sj.ijo.0800773 ID - Hauner1998 ER -