Figure 1
From: Fibronectin glycation increases IGF-I induced proliferation of human aortic smooth muscle cells
Characterization of AGE-modified FN (AGE-FN). Fluorescence of the AGE compound FFI observed at 440 nm after excitation at 375 nm (Panel A). Fibronectin (FN) structural modification secondary to advanced glycation was established by assessing bityrosine formation (400 nm upon excitation at 325 nm) (Panel B) and tryptophan quenching (334 nm upon excitation at 275 nm) (Panel C).