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Table 1 Expression and activities of ADMA-related enzymes in the white adipose and skeletal muscle tissues of control Wistar and diabetic GK rats

From: Activities of asymmetric dimethylarginine-related enzymes in white adipose tissue are associated with circulating lipid biomarkers

 

PRMT1 expression

PRMT1 activity

   

Wistar

GK

Wistar

GK

  

Visceral fat

100 ± 2

75.7 ± 6.1**

100 ± 3

41.9 ± 6.4**

  

Subcutaneous fat

100 ± 4

79.0 ± 3.3**

100 ± 5

73.4 ± 6.4**

  

Skeletal muscle (11 weeks of age)

100 ± 4

109 ± 9

100 ± 4

102 ± 3

  

Skeletal muscle (20 weeks of age)

100 ± 2

117 ± 2

100 ± 3

125 ± 4**

  

DDAH1 expression

DDAH2 expression

DDAH activity

Wistar

GK

Wistar

GK

Wistar

GK

Visceral fat

100 ± 9

138 ± 9

100 ± 7

68.7 ± 6.5**

100 ± 7

259 ± 19**

Subcutaneous fat

100 ± 10

139 ± 5*

100 ± 5

73.5 ± 3.3*

100 ± 8

245 ± 33*

Skeletal muscle (11 weeks of age)

100 ± 10

90.8 ± 2.3

100 ± 21

136 ± 11

100 ± 9

91.4 ± 9.3

Skeletal muscle (20 weeks of age)

100 ± 5

96.0 ± 5.4

100 ± 5

144 ± 7**

100 ± 5

109 ± 6

  1. Values represent the mean ± SEM of five to ten rats in each group and are expressed as the percentile for the relative level of expression or activity to that of the age-matched Wistar controls. *p ≪ 0.05, **p ≪ 0.01 vs. the controls.