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Table 1 Histopathological findings in insulin-induced circumscript lipoatrophy, as reported in the literature.

From: Relapsing insulin-induced lipoatrophy, cured by prolonged low-dose oral prednisone: a case report

Previous reports, author Reeves[1] Jermendy[5] Lopez[10] Chantelau[3] present case
cases,n 5 1 4 1  
Skin:      
immunofluorescence staining* positive negative not analysed negative not analysed
mononuclear cell infiltration mild none not analysed mild not analysed
Subcutaneous tissue:      
fat tissue atrophy present absent? present present present
focal fibrosis absent? absent? present present present
lipoblast-like adipocytes absent present absent absent absent
capillary proliferation absent present absent absent absent
immunofluorescence staining* not analysed not analysed negative negative not analysed
lymphocyte infiltration absent not analysed mild mild not analysed
eosinophils infiltration absent not analysed present absent not analysed
mast cells infiltration absent not analysed present absent not analysed
  1. *for IgG, IgA, IgM, C1, C3, and fibrin, or amyloid, respectively