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Table 3 Clinical and biochemical parameters in thyroid autoimmunity positive and thyroid autoimmunity negative patients with T1DM

From: Helicobacter pylori infection might be responsible for the interconnection between type 1 diabetes and autoimmune thyroiditis

Parameters

Thyroid autoimmunity positive (n = 92)

Thyroid autoimmunity negative(n = 70)

OR

95% CI

P- value

Age (years)

19.37 ± 2.8

19.32 ± 2.45

-

-

0.92

Duration of diabetes (years)

7.37 ± 2.87

7.12 ± 2.79

-

-

0.54

HbA1c (%)

8.2 ± 1.7

7.85 ± 1.95

  

0.15

H. pylori positive(+)

92.3% (85/92)

61.4% (43/70)

7.6

2.8: 12.6

< 0.001*

Anti- HP IgG (+)

70.6% (65/92)

48.5% (34/70)

2.55

1.27:5.15

0.007*

Anti- HP IgA (+)

86.9% (80/92)

57.1% (40/70)

5

2.18:11.6

0.001*

  1. Data are expressed as mean ± standard deviation, numbers or percentages. OR; odds ratio, CI; confidence interval, HbA1c; glycated hemoglobin, Anti- H.P IgG; anti-helicobacter pylori IgG, Anti- H.P IgA; anti-helicobacter pylori IgA, * P is significant if < 0.05.