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Table 2 Clinical and biochemical parameters in H pylori positive and H pylori negative patients with T1DM

From: Helicobacter pylori infection might be responsible for the interconnection between type 1 diabetes and autoimmune thyroiditis

Parameters H.P positive (n = 128) H.P negative (n = 34) OR 95% CI P- value
Age (years) 20.1 ± 4.6 19.8 ± 4.34 - - 0.72
Duration of diabetes (years) 8.9 ± 8.6 4.22 ± 2.35 - - < 0.001*
HbA1c (%) 8.3 ± 1.58 6.8 ± 2.3    < 0.001*
Thyroid autoimmunity (+) 63.2% (81/128) 32.3% (11/34) 3.6 1.5:8.7 0.002*
Anti-TPO (+) 28.9% (37/128) 11.7% (4/34) 3.05 0.93: 11.1 0.04*
Anti-Tg (+) 53.1% (68/128) 26.4% (9/34) 4.7 1.87: 12.2 < 0.001*
  1. Data are expressed as mean ± standard deviation, numbers or percentages. H.P; helicobacter pylori, OR; odds ratio, CI; confidence interval, HbA1c; glycated hemoglobin, Anti-TPO; anti-thyroid peroxidase, Anti-Tg; anti-thyroglobulin, * P is significant if < 0.05.