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Table 2 Clinical and biochemical parameters in H pylori positive and H pylori negative patients with T1DM

From: Helicobacter pylori infection might be responsible for the interconnection between type 1 diabetes and autoimmune thyroiditis

Parameters

H.P positive

(n = 128)

H.P negative

(n = 34)

OR

95% CI

P- value

Age (years)

20.1 ± 4.6

19.8 ± 4.34

-

-

0.72

Duration of diabetes (years)

8.9 ± 8.6

4.22 ± 2.35

-

-

< 0.001*

HbA1c (%)

8.3 ± 1.58

6.8 ± 2.3

  

< 0.001*

Thyroid autoimmunity (+)

63.2% (81/128)

32.3% (11/34)

3.6

1.5:8.7

0.002*

Anti-TPO (+)

28.9% (37/128)

11.7% (4/34)

3.05

0.93: 11.1

0.04*

Anti-Tg (+)

53.1% (68/128)

26.4% (9/34)

4.7

1.87: 12.2

< 0.001*

  1. Data are expressed as mean ± standard deviation, numbers or percentages. H.P; helicobacter pylori, OR; odds ratio, CI; confidence interval, HbA1c; glycated hemoglobin, Anti-TPO; anti-thyroid peroxidase, Anti-Tg; anti-thyroglobulin, * P is significant if < 0.05.