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Table 2 Cox proportional hazard model of baseline risk factors for development of microalbuminuria in 122 patients with type 1 diabetes who were followed for seven years

From: Progression to microalbuminuria in patients with type 1 diabetes: a seven-year prospective study

Baseline Data Univariate Analysis Hazard Ratio (95% CI) p value Multivariate Model Hazard ratio (95% CI) p value
Age 1.03 (1.00-1.06) 0.026   
Age at diagnosis 1.03 (0.99-1.06) 0.123   
Gender 0.92 (0.52-1.63) 0.779   
Duration of diabetes 1.03 (0.98-1.07) 0.247   
Insulin dose 1.34 (0.77-2.32) 0.302   
AER 1.01 (0.96-1.07) 0.660   
Systolic blood pressure 1.02 (0.99-1.04) 0.170   
Diastolic blood pressure 1.02 (0.99-1.06) 0.210   
A1c 1.02 (0.87-1.20) 0.810   
Two-hour post-prandial glycemia 0.99 (0.99-1.00) 0.294   
Fasting glycemia 1.00(0.99-1.01) 0.234   
BMI 1.12 (1.03-1.22) 0.006 1.12 (1.03-1.21) 0.01
Total cholesterol level 1.01 (1.0-1.01) 0.042   
HDL cholesterol level 0.99 (0.98-1.02) 0.930   
Triglyceride level 1.00 (0.99-1.01) 0.08   
LDL cholesterol level 1.01 (1.00-1.01) 0.045   
Cholesterol/HDL ratio 1.32 (1.07-1.63) 0.010 1.32 (1.05-1.67) 0.019
LDL/HDL ratio 1.26 (0.97-1.62) 0.079   
Presence of retinopathy 1.37 (0.33-5.68) 0.667   
Family history of type 2 diabetes 2.03 (1.06-3.92) 0.044   
  1. BMI, body mass index; AER, albumin excretion rate; A1c, glycated hemoglobin; HDL, high density lipoprotein; LDL, low density lipoprotein