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Table 1 Age adjusted association of metabolic syndrome and other related biomarkers in menopausal transition (mean ± SD)

From: Metabolic syndrome in menopausal transition: Isfahan Healthy Heart Program, a population based study

Variables Pre-menopausal (n = 303) Menopausal (n = 233) Post-menopausal (n = 987) P value*
Age (years) 47.2 ± 2.1 51.5 ± 5.8 61.6 ± 8.5 < 0.001
Systolic blood pressure (mmHg) 120.2 ± 20.2 125.2 ± 23 132.4 ± 22.1 0.030
Diastolic blood pressure (mmHg) 77.8 ± 11.8 80.3 ± 12.8 82.5 ± 11.8 0.008
Fasting plasma glucose (mg/dl) 88.7 ± 29.7 91.2 ± 34 95.1 ± 38.2 0.393§
2 h-post-prandial glucose (mg/dl) 115 ± 53.4 121 ± 67.4 127.3 ± 70.2 0.011§
Total Cholesterol (mg/dl) 209.8 ± 44.6 233.6 ± 54.6 233.3 ± 50.6 < 0.001
LDL-C (mg/dl) 127.2 ± 38.2 142.8 ± 47.3 142.5 ± 43.5 0.004
Triglycerides (mg/dl) 176.1 ± 98.9 213.7 ± 118.1 207.8 ± 104.9 < 0.001
HDL-C (mg/dl) 48.3 ± 10.1 50.4 ± 11 49.5 ± 10.8 0.121
Waist (cm) 97.6 ± 12.5 97.2 ± 13.4 98.5 ± 12.3 0.197
Waist to hip ratio 0.92 ± 0.07 0.93 ± 0.08 0.95 ± 0.07 0.391
Body mass index 28.6 ± 4.7 28.3 ± 5.1 27.6 ± 4.5 0.932
Anti diabetes medication 12(4%) 13(5.6%) 115(11.7%) 0.003
Anti hypertension medication 35(11.6%) 48(20.6%) 324(32.9%) 0.153
Global Dietary Index 0.90 ± 0.23 0.87 ± 0.23 0.84 ± 0.27 0.630
Leisure Time Physical Activity 62.40 ± 82.37 66.19 ± 88.04 62.09 ± 82.54 0.482
  1. * Age adjusted P-value § Adjusted for Anti diabetes medication in addition to age
  2. †Post hoc test did not find significant relationship between early menopausal and Post- Menopausal group