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Table 3 Effect of HFD and taurine supplementation on fasting serum lipids, TAC, PON, NOx and plasma Hcy:

From: Effect of taurine supplementation on hyperhomocysteinemia and markers of oxidative stress in high fructose diet induced insulin resistance

Parameter

Group

 

Control

Taurine

Fructose-Fed

Fructose-Fed + Taurine

TGs (mg/dl)

70.47 ± 8.95

79.53 ± 7.94

262.16 ± 22.47a,b

203.17 ± 16.45a,b,c

T-Chol (mg/dl)

99.86 ± 2.21

93.32 ± 5.22

136.43 ± 1.92a,b

121.37 ± 2.59a,b,c

LDL-C (mg/dl)

29.30 ± 1.64

29.98 ± 3.22

57.27 ± 2.16a,b

45.04 ± 2.22a,b,c

HDL-C (mg/dl)

42.22 ± 1.20

41.35 ± 2.36

52.03 ± 1.40a,b

53.71 ± 1.79a,b

Atherogenic index

2.37 ± 0.03

2.27 ± 0.06

2.63 ± 0.06a,b

2.27 ± 0.07c

Hcy (μmol/l)

10.31 ± 0.65

11.02 ± 0.53

13.89 ± 0.48a,b

14.23 ± 0.62a,b

TAC (mmol/L)

3.05 ± 0.17

3.07 ± 0.11

2.44 ± 0.15a,b

3.11 ± 0.17c

PON (U/ml)

167.30 ± 9.08

160.92 ± 9.07

117.49 ±4.99a,b

148.51 ± 6.75c

NOx (μM)

21.70 ± 2

21.35 ± 1.66

41.97 ± 2.47a,b

26.82 ± 2.21c

  1. Values are expressed as mean ± S.E.M. Number of animal per group n = 8.
  2. HFD, high fructose diet; TGs, triglycerides; T-Chol, total cholesterol; LDL-C, low density lipoprotein cholesterol; HDL-C, high density lipoprotein cholesterol; TAC, total antioxidant capacity: PON, paraoxonase activity: NOx, nitric oxide metabolites: Hcy, homocysteine.
  3. (a) Significant different from control group (P ≤ 0.05).
  4. (b) Significant different from taurine group (P ≤ 0.05).
  5. (c) Significant different from fructose-fed group (P ≤ 0.05).
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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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