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Table 4 Frequency of external and skeletal anomalies in fetuses from mildly diabetic (STZ) and non-diabetic (control) rats at term pregnancy.

From: Evaluation of neonatally-induced mild diabetes in rats: Maternal and fetal repercussions

 

Groups

 

Control

(n= 15)

STZ

(n= 13)

Number of fetuses examined for external anomalies

198

138

Number of fetuses with external anomalies

0

0

Number of fetuses examined for skeletal anomalies

81 (100%)

55 (100%)

   Abnormal shaped sternebrae

2/81 (2%)

5/55 (9%)*

   Extra ossification site of sternebrae

0/81(0%)

1/55 (2%)

   Incomplete ossification of vertebrae

1/81 (1%)

0/55 (0%)

   Absent cervical nuclei

50/81 (62%)

57/55 (104%)*

   Bipartite cervical nuclei

3/81 (4%)

1/55 (2%)

   Incomplete ossification of cervical nuclei

5/81 (6%)

5/55 (9%)

  1. *p < 0.05 - statistically significant difference compared to control group (Chi Square Test).