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Table 9 action profile of human insulin and human insulin analogs

From: Algorithm for the treatment of type 2 diabetes: a position statement of Brazilian Diabetes Society

Insulin Type Onset Action peak Duration of action
Rapid-acting insulin analogs Glulisine
<5-15 minutes 1 hour 4 hours
<15 minutes 0.5-1.5 hour 2-4 hours
5-10 minutes 1-3 hours 3-5 hours
Short acting insulin Regular
(Novolin® R, Humulin® R)
30-60 minutes 2-3 hours 3-6 hours
Intermediate acting insulin NPH (Novolin® N Humulin® N) 2-4 hours 4-10 hours 10-16 hours
Long-acting insulin analogs Glargine
1-2 hours None Up to 24 hours
1-2 hours None Up to 24 hours
  1. This table presents only a partial list of commercial medications of various drugs and does not represent a specific recommendation of any commercial brand.