Table 7 Partial list of oral antidiabetic drugs used in combination therapy: two substances in separate pills
From: Algorithm for the treatment of type 2 diabetes: a position statement of Brazilian Diabetes Society
Therapeutic classes | Chemical Denomination | Commercial Denomination | Action and Dosage Mechanism |
|---|---|---|---|
sulffonylurea + biguanide | glimepiride + metformin | Amaryl Flex® Sanofi-Aventis | Long acting secretagogue of insulin (glimepiride) + peripheral action insulin sensitizer (metformin). Dosage: glimepiride - 1 mg and 2 mg + metformin - 500 mg. |
glinide + biguanide | nateglinide + metformin | Starform® Novartis | Short-acting secretagogue of insulin (nateglinide) + peripheral action insulin sensitizer (metformin). Dosage: nateglinide - 120 mg + metformin - 500 mg and 850 mg. |