Table 7 Partial list of oral antidiabetic drugs used in combination therapy: two substances in separate pills
From: Algorithm for the treatment of type 2 diabetes: a position statement of Brazilian Diabetes Society
| Therapeutic classes | Chemical Denomination | Commercial Denomination | Action and Dosage Mechanism |
|---|---|---|---|
|
sulffonylurea + biguanide |
glimepiride + metformin |
Amaryl Flex® Sanofi-Aventis |
Long acting secretagogue of insulin (glimepiride) + peripheral action insulin sensitizer (metformin). Dosage: glimepiride - 1 mg and 2 mg + metformin - 500 mg. |
|
glinide + biguanide |
nateglinide + metformin |
Starform® Novartis |
Short-acting secretagogue of insulin (nateglinide) + peripheral action insulin sensitizer (metformin). Dosage: nateglinide - 120 mg + metformin - 500 mg and 850 mg. |