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Table 7 Partial list of oral antidiabetic drugs used in combination therapy: two substances in separate pills

From: Algorithm for the treatment of type 2 diabetes: a position statement of Brazilian Diabetes Society

Therapeutic classes Chemical Denomination Commercial Denomination Action and Dosage Mechanism
sulffonylurea
+
biguanide 		glimepiride
+
metformin 		Amaryl Flex®
Sanofi-Aventis 		Long acting secretagogue of insulin (glimepiride) + peripheral action insulin sensitizer (metformin).
Dosage: glimepiride - 1 mg and 2 mg + metformin - 500 mg.
glinide
+
biguanide 		nateglinide
+
metformin 		Starform®
Novartis 		Short-acting secretagogue of insulin (nateglinide) + peripheral action insulin sensitizer (metformin).
Dosage: nateglinide - 120 mg + metformin - 500 mg and 850 mg.
  1. This table presents only a partial list of commercial medications of various drugs and does not represent a specific recommendation of any commercial brand.
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