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Table 1 Effect of different immunomodulatory therapies on insulin-free period in patients with newly diagnosed type 1 diabetes mellitus

From: Stem cell therapy for type 1 diabetes mellitus: a review of recent clinical trials

Immunomodulating therapy

Treatment length

Number of patients free from/total number of patients

Period free from insulin (average)

Prednisone2

12 months (daily use)

4/17

3 months

Prednisone + azathioprine4

12 months (daily use)

10/20

1 week

Azathioprine3

12 months (daily use)

0/24

0

Ciclosporin5

24 months (daily use)

53/122

10 months

Antibody anti-CD36

E.V. application 6 days in a row

0

0

Heat shock protein7

1 S.C. application in time 0, + 1 and + 6 months

0

0

Anti-thymocyte globulin8

E.V. Applications 4 days in a row

0

0

Glutamic acid decarboxylase9

2 subcutaneous applications with 1-month interval

0

0