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Table 1 Effect of different immunomodulatory therapies on insulin-free period in patients with newly diagnosed type 1 diabetes mellitus

From: Stem cell therapy for type 1 diabetes mellitus: a review of recent clinical trials

Immunomodulating therapy Treatment length Number of patients free from/total number of patients Period free from insulin (average)
Prednisone2 12 months (daily use) 4/17 3 months
Prednisone + azathioprine4 12 months (daily use) 10/20 1 week
Azathioprine3 12 months (daily use) 0/24 0
Ciclosporin5 24 months (daily use) 53/122 10 months
Antibody anti-CD36 E.V. application 6 days in a row 0 0
Heat shock protein7 1 S.C. application in time 0, + 1 and + 6 months 0 0
Anti-thymocyte globulin8 E.V. Applications 4 days in a row 0 0
Glutamic acid decarboxylase9 2 subcutaneous applications with 1-month interval 0 0