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Table 2 Concentrations of inflammatory markers by polymorphisms in the TCF7L2 genea

From: TCF7L2 polymorphisms and inflammatory markers before and after treatment with fenofibrate

Variable rs12255372 (G>T) rs7903146 (C>T)
Before fenofibrate GG GT TT CC CT TT
n 512 390 115 514 398 113
CRP, mg/dL 0.23 (0.37) 0.25 (0.59) 0.33 (0.82) 0.23 (0.36) 0.25 (0.57) 0.31 (0.79)
IL-2 sR alpha, pg/mL 1014 (375) 1035 (353) 991 (332) 1021 (384) 1029 (350) 990 (324)
IL-6, pg/mL 2.04 (3.90) 1.88 (2.31) 1.88 (1.98) 2.10 (4.16) 1.74 (1.28) 2.00 (2.39)
TNF-alpha, pg/mL 3.25 (2.48) 3.73 (8.07) 3.35 (2.79) 3.28 (2.48) 3.68 (7.99) 3.36 (2.72)
MCP-1, pg/mL 208 (58) 212 (78) 205 (51) 209 (58) 210 (78) 207 (49)
After fenofibrate       
n 373 300 89 373 307 96
hsCRP, mg/dL 0.22 (0.35) 0.29 (0.53) 0.30 (0.61) 0.22 (0.37) 0.30 (0.54) 0.25 (0.50)
IL-2 sR alpha, pg/mL 1161 (539) 1186 (580) 1086 (354) 1169 (541) 1186 (573) 1063 (336)
IL-6, pg/mL 2.22 (4.23) 2.24 (2.68) 1.86 (2.08) 2.24 (4.34) 2.12 (2.21) 1.99 (2.19)
TNF-alpha, pg/mL 3.52 (2.36) 3.99 (5.99) 3.64 (2.53) 3.55 (2.36) 3.96 (5.93) 3.58 (2.46)
MCP-1, pg/mL 179 (94) 186 (102) 197 (80) 179 (93) 187 (103) 197 (77)
  1. a Values are means and SD; there were no significant differences across genotypes (P > 0.05).