Volume 7 Supplement 1

20th Brazilian Diabetes Society Congress

Open Access

Evaluation of restless legs syndrome symptoms in patients with and without the diagnosis of type 2 diabetes mellitus

  • Arthur Onofre Beltran Filho1Email author,
  • Guilherme Andreas Jung1,
  • Leandro Vicente Zoehler1,
  • Josue Cortez1 and
  • Aline Vieira Scarlatelli Lima1
Diabetology & Metabolic Syndrome20157(Suppl 1):A89

DOI: 10.1186/1758-5996-7-S1-A89

Published: 11 November 2015

Background

Restless legs syndrome (RLS) is a neurological sleep disorder. Literature suggests association between RLS and diabetes, but few studies have been done evaluating the association between these conditions[1].

Objective

Evaluate the prevalence of RLS symptoms in patients with and without the diagnosis of Type 2 Diabetes Mellitus (DM2).

Materials and methods

Case control study. 112 individuals were studied, 28 with DM2 (cases) and 84 without DM2 (controls), in a medical clinic specialities at Tubarão, Brazil. They answered a questionnaire with socio demographic questions, information about diabetes and to the four minimum criteria, defined by The International Restless Legs Syndrome Study Group (IRLSSG), for RLS diagnosis[2]. Furthermore, they were subjected to the Epworth Sleepiness scale and the IRLSSG rating scale, both translated and validated to Portuguese[3, 4].

Results

Among the cases, 21.4% presented RLS, compared to 14.3% in controls (p=0.269). The group with DM2 showed higher prevalence of Excessive daytime Sleepiness (EDS) (21.4% vs. 13.1%; p=0.219), and had higher scores in the IRLSSG rating scale (23,3±11,3 vs. 15,7±6,5; p=0.086). Correlating severity of RLS with glycemia, we obtained a Pearson correlation of 0.698 (p=0.003).

Conclusions

DM2 patients have a higher, but non-significant prevalence of RLS symptoms and EDS than the non-diabetics. It has been found a correlation between RLS severity and glycemia.

Authors’ Affiliations

(1)
Universidade do Sul de Santa Catarina

References

  1. Innes KE, Selfe TK, Agarwal P: Restless legs syndrome and conditions associated with metabolic dysregulation, sympathoadrenal dysfunction, and cardiovascular disease risk: a systematic review. Sleep Med Rev. 2012, 16 (4): 309-39.PubMedView ArticleGoogle Scholar
  2. Allen RP, Picchietti D, Hening WA, Trenkwalder C, Walters AS, Montplaisi J, et al: Restless legs syndrome: diagnostic criteria, special considerations, and epidemiology. A report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institutes of Health. Sleep Med. 2003, 4 (2): 101-19.PubMedView ArticleGoogle Scholar
  3. Bertolazi AN, Fagondes SC, Hoff LS, Pedro VD, Barreto M, Saldanha S, et al: Portuguese-language version of the Epworth sleepiness scale: validation for use in Brazil. J Bras Pneumol. 2009, 35 (9): 877-83.PubMedView ArticleGoogle Scholar
  4. Masuko AH, Carvalho LBC, Machado MAC, Morais JF, Prado LBF, Prado GF: Translation and validation into the Brazilian Portuguese of the restless legs syndrome rating scale of the International Restless Legs Syndrome Study Group. Arq Neuropsiquiatr. 2008, 66 (4): 832-6.PubMedView ArticleGoogle Scholar

Copyright

© Filho et al. 2015

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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