A nonlinear relationship between the triglycerides to high-density lipoprotein cholesterol ratio and stroke risk: an analysis based on data from the China Health and Retirement Longitudinal Study

Zhang, Shike; Cao, Changchun; Han, Yong; Hu, Haofei; Zheng, Xiaodan

doi:10.1186/s13098-024-01339-3

Table 1 The baseline characteristics of participants

From: A nonlinear relationship between the triglycerides to high-density lipoprotein cholesterol ratio and stroke risk: an analysis based on data from the China Health and Retirement Longitudinal Study

TG/HDL-C ratio	Q1 (≤ 1.32)	Q2 (1.32 to ≤ 2.11)	Q3 (2.11 to ≤ 3.56)	Q4 (> 3.56)	P-value
Participants	2539	2542	2542	2541
Gender					< 0.001^b
Male	1317 (51.87%)	1173 (46.14%)^a	1126 (44.30%)^a	1130 (44.47%)^a
Female	1222 (48.13%)	1369 (53.86%)	1416 (55.70%)	1411 (55.53%)
Age (years)	59.89 ± 9.76	59.32 ± 9.48^a	59.04 ± 9.11^a	58.45 ± 8.96^a	< 0.001^d
Drinking status					< 0.001^b
Never drinkers	312 (12.29%)	350 (13.77%)^a	378 (14.87%)^a	344 (13.54%)^a
Ever drinkers	1398 (55.06%)	1580 (62.16%)	1609 (63.30%)	1633 (64.27%)
Current drinkers	829 (32.65%)	612 (24.08%)	555 (21.83%)	564 (22.20%)
Smoking status					< 0.001^b
Never smokers	1469 (57.86%)	1571 (61.80%)^a	1605 (63.14%)^a	1605 (63.16%)^a
Ever smokers	221 (8.70%)	204 (8.03%)	217 (8.54%)	240 (9.45%)
Current smokers	849 (33.44%)	767 (30.17%)	720 (28.32%)	696 (27.39%)
Physical activity					< 0.001^b
No	790 (31.11%)	896 (35.25%)^a	945 (37.18%)^a	962 (37.86%)^a
Yes	1749 (68.89%)	1646 (64.75%)	1597 (62.82%)	1579 (62.14%)
Drugs for cardiovascular prevention					< 0.001^b
No	2379 (93.70%)	2359 (92.80%)	2338 (91.97%)^a	2280 (89.73%)^a
Yes	160 (6.30%)	183 (7.20%)	204 (8.03%)	261 (10.27%)
Hypertension					< 0.001^b
No	1678 (66.09%)	1589 (62.51%)^a	1409 (55.43%)^a	1249 (49.15%)^a
Yes	861 (33.91%)	953 (37.49%)	1133 (44.57%)	1292 (50.85%)
SBP (mmHg)	128.03 ± 21.01	129.23 ± 20.94^a	131.77 ± 21.70^a	133.32 ± 21.31^a	0.011^d
DBP (mmHg)	73.98 ± 12.04	74.83 ± 11.71^a	76.45 ± 12.15^a	77.98 ± 12.01^a	< 0.001^d
BMI (kg/m²)	22.08 ± 3.42	22.98 ± 3.83^a	24.00 ± 3.95^a	25.04 ± 3.89^a	< 0.001^d
TG/HDL-C ratio	0.96 ± 0.23	1.69 ± 0.23^a	2.73 ± 0.41^a	6.41 ± 3.13^a	< 0.001^d
HDL-C (mg/dL)	67.26 ± 14.34	54.13 ± 10.12^a	46.88 ± 8.66^a	37.56 ± 7.91^a	< 0.001^d
TG (mg/dL)	62.59 ± 15.09	91.13 ± 18.44^a	127.07 ± 26.02^a	229.07 ± 89.30^a	< 0.001^d
LDL-C (mg/dL)	111.06 ± 29.89	119.04 ± 32.66^a	123.42 ± 34.41^a	113.94 ± 37.98^a	< 0.001^d
TC (mg/dL)	188.07 ± 34.74	189.16 ± 36.70	194.14 ± 37.53^a	200.17 ± 41.83^a	< 0.001^d
CRP (mg/L)	0.75 (0.44–1.74)	0.91 (0.52–1.88)^a	1.08 (0.58–2.25)^a	1.32 (0.72–2.63)^a	< 0.001^c
Scr (mg/dL)	0.78 ± 0.32	0.77 ± 0.22	0.78 ± 0.20	0.80 ± 0.20^a	< 0.001^d
FPG (mg/dL)	102.23 ± 23.48	105.34 ± 28.41^a	109.09 ± 34.61^a	120.99 ± 45.84^a	< 0.001^d
HbA1c (%)	5.13 ± 0.61	5.19 ± 0.70^a	5.25 ± 0.82^a	5.40 ± 0.98^a	< 0.001^d
Cystatin C (mg/L)	1.01 ± 0.31	1.03 ± 0.27	1.01 ± 0.27	0.96 ± 0.26^a	< 0.001^d
UA (mg/dL)	4.24 ± 1.16	4.32 ± 1.22^a	4.45 ± 1.24^a	4.79 ± 1.31^a	< 0.001^d

Values are n (%) or mean ± SD or median (quartile)
TG/HDL-C ratio ratio of triglyceride to high-density lipoprotein cholesterol, SBP systolic blood pressure, DBP diastolic blood pressure, BMI body mass index, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, TC total cholesterol, TG triglycerides, Scr serum creatinine, CRP C-reactive protein, FPG fasting plasma glucose, HbA1c glycosylated hemoglobin, UA uric acid
^aRepresents other groups (Q2, Q3, Q4) compared with Q1, P < 0.05
^bUsed the χ² test
^cApplied the Kruskal–Wallis
^dUsed the one-way ANOVA test

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