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Table 3 Cox regression models with total mortality as outcome for patients for patients aged ≥45 years with diagnoses of AF and diabetes mellitus ( n= 2,413) attending the 75 PHCCs between January 1st2001 and December 31st2007, stratified by age: 45–79 years (n = 1,704) and 80–104 years (n = 709)

From: Effects of prescribed antithrombotics and other cardiovascular pharmacotherapies on all-cause mortality in patients with diabetes and atrial fibrillation – a cohort study from Sweden using propensity score analyses

 

Patients aged <80 years

Patients aged ≥80 years

All patients

 

Full model

Full model

Full model

 

HR (95% CI)

HR (95% CI)

HR (95% CI)

Antithrombotic drugs

   

  Antiplatelets vs. no treatment

0.86 (0.43-1.72)

0.47 (0.26-0.87)

0.70 (0.45-1.09)

  Anticoagulants vs. no treatment

0.40 (0.17-0.91)

0.49 (0.24-1.00)

0.45 (0.26-0.77)

  Anticoagulants vs. antiplatelets

0.44 (0.25-0.78)

1.02 (0.60-1.73)

0.62 (0.42-0.92)

Digitalis

0.81 (0.54-1.23)

0.90 (0.60-1.35)

0.83 (0.62-1.11)

Loop diuretics

2.42 (1.36-4.33)

1.02 (0.60-1.73)

1.55 (1.06-2.28)

Thiazides

0.98 (0.59-1.63)

0.89 (0.55-1.44)

0.93 (0.66-1.32)

Aldosterone antagonists

1.20 (0.76-1.88)

1.22 (0.79-1.88)

1.29 (0.94-1.77)

Beta blockers

0.62 (0.40-0.97)

0.73 (0.49-1.10)

0.67 (0.49-0.90)

RAS-blocking agents

1.08 (0.65-1.78)

1.23 (0.79-1.93)

1.16 (0.83-1.62)

Calcium receptor-blocking agents

1.06 (0.69-1.63)

1.20 (0.77-1.87)

1.10 (0.81-1.49)

Statins

0.45 (0.29-0.71)

0.77 (0.47-1.26)

0.56 (0.40-0.78)

  1. Full model is adjusted for a propensity score comprising sex, age group, co-morbidities, educational level, marital status and for all pharmacotherapies. HRs and 95% CIs are shown. Statistically significant HRs are highlighted in bold.